Protective Efficacy of Cell-Free-Antigen of Actinobacillus pleuropneumoniae in Mice.
نویسندگان
چکیده
منابع مشابه
Evaluation of multicomponent recombinant vaccines against Actinobacillus pleuropneumoniae in mice
BACKGROUND Porcine contagious pleuropneumonia (PCP) is a highly contagious disease that is caused by Actinobacillus pleuropneumoniae (APP) and characterized by severe fibrinous necrotizing hemorrhagic pleuropneumonia, which is a severe threat to the swine industry. In addition to APP RTX-toxins I (ApxI), APP RTX-toxin II (ApxII), APP RTX-toxin III (ApxIII) and Outer membrane protein (OMP), ther...
متن کاملSerological characterisation of Actinobacillus pleuropneumoniae
In the most recent study on the serological characterisation of Australian isolates of A pleuropneumoniae, a large percentage of isolates either gave cross-reactions with serovars 3 and 6 (47/256 isolates) or no reaction at all (91/256 isolates).11 This study was performed using slide agglutination and GD, techniques which had performed effectively in the past.5 The high incidence of isolates t...
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orcine pleuropneumonia is caused by Actinobacillus pleuropneumoniae. This organism is thought to be transmitted mainly through direct contact, usually after asymptomatic carrier pigs are introduced into a herd. The possibility of indirect transmission has only occasionally been raised.1,2 Nicolet reported that the source of infection in Swiss specific-pathogen-free (SPF) herds was often unknown...
متن کاملEfficacy of a cell extract from Actinobacillus (Haemophilus) pleuropneumoniae serotype 1 against disease in swine.
We partially characterized a cell extract (CE) from Actinobacillus pleuropneumoniae serotype 1 and used the CE to test the efficacy of secreted proteins against disease. Secreted products from 4-h culture supernatants were precipitated with 20% polyethylene glycol. Analysis of the CE indicated the presence of protein, endotoxin, and carbohydrate. Hemolytic activity to bovine erythrocytes and cy...
متن کاملActinobacillus pleuropneumoniae-induced thymic lesions in mice and pigs.
Actinobacillus pleuropneumoniae produces several hemolysins/cytotoxins that may be important in the pathogenesis of acute lesions. Little is known, however, about the role of these virulence factors in chronic disease or the carrier state. We investigated the effects of live bacterial infection and transthoracic injection of a sterile culture supernatant on primary lymphoid organs and lymphocyt...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1995
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.57.727