Protective effects of polysialic acid on proteolytic cleavage of FGF2 and proBDNF/BDNF
نویسندگان
چکیده
منابع مشابه
Protective effects of polysialic acid on proteolytic cleavage of FGF2 and proBDNF/BDNF.
Polysialic acid (polySia) is a linear polymer of sialic acid that modifies neural cell adhesion molecule (NCAM) in the vertebrate brain. PolySia is a large and exclusive molecule that functions as a negative regulator of cell-cell interactions. Recently, we demonstrated that polySia can specifically bind fibroblast growth factor 2 (FGF2) and BDNF; however, the protective effects of polySia on t...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2015
ISSN: 0959-6658,1460-2423
DOI: 10.1093/glycob/cwv049