Protective effects of nobiletin on rotenone-induced neuronal dysfunction is mediated with complex 1 regulation
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چکیده
منابع مشابه
Pramipexole protective effect on rotenone induced neurotoxicity in mice
Introduction: Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find new capacity for this drug rather than symptomatic effect. Materials and Methods: A chronic rotenone model with daily oral dose of 30mg/kg was induced in mice. Pramipexole was tried in a new approach where the treatment began in the middle of rotenone course with oral dose 1m...
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Background and Aims: Cadmium chloride causes renal dysfunction. The present study aimed to investigate the protective effects of hydroalcoholic extract of Alcea rosea aerial parts on cadmium chloride-induced renal dysfunction in male rats. Materials and Methods: In this experimental study, 54 adult male Wistar rats were assigned to six groups (n=9 in each group). The control group, the sham gr...
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Some citrus flavonoids have been reported to possess antioxidant activities that moderate endothelial dysfunction and show protective effects on cardiovascular disease. We have investigated the protective effects of nobiletin (5,6,7,8,3’,4’-hexamethoxy flavone) derived from the peel of Citrus depressa Hayata (Shiikuwasha), a citrus fruit produced in Okinawa prefecture in Japan on hypertension a...
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ژورنال
عنوان ژورنال: IBRO Reports
سال: 2019
ISSN: 2451-8301
DOI: 10.1016/j.ibror.2019.07.1736