Protective effect of creatine on amikacin-induced ototoxicity
نویسندگان
چکیده
منابع مشابه
The Protective Effect of Cortexin on Cisplatin-Induced Ototoxicity.
OBJECTIVE The aim of this report is to evaluate whether cortexin provides any protective activity against ototoxicity of cisplatin. MATERIALS AND METHODS The study was performed on 30 healthy adult Wistar Albino rats, and rats were randomly divided into three groups of ten. Group I (Control group) was given intraperitoneal (ip) saline solution 1 mL/day. Group II (Cisplatin group) was given ip...
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One of the major adverse effects of cisplatin chemotherapy is hearing loss. Cisplatin-induced ototoxicity hampers treatment because it often necessitates dose reduction, which decreases cisplatin efficacy. This study was performed to investigate the effect of Tempol on cisplatin-induced ototoxicity in an auditory cell line, House Ear Institute-Organ of Corti 1 (HEI-OC1). Cultured HEI-OC1 cells ...
متن کاملEvaluation of the Protective Effect of Beta Glucan on Amikacin Ototoxicity Using Distortion Product Otoacoustic Emission Measurements in Rats
OBJECTIVES This experimental study investigated the possible protective effect of beta glucans on amikacin ototoxicity. METHODS Thirty-eight rats with normal distortion product otoacoustic emissions (DPOAEs) were divided into four groups. Group K was the control group. Group A was injected intramuscularly (i.m.) with amikacin 600 mg/kg/day between days 1-15. Group AB was given beta glucan gav...
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ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2020
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2020.09.002