Protection of organs other than the heart by remote ischemic conditioning

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Remote ischemic conditioning.

In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and render remote tissues and organs resistant to ischemia/reperfusion injury. The peripheral stimulus can be chemical, mechanical, or electrical and involves activation of peripheral sensory nerves. The signal transfer to the ...

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Ischemic heart disease is the leading cause of death and morbidity in the world, and ST-segment elevation myocardial infarction (STEMI) remains associated with a significant mortality rate and complications noted at 1-year follow-up, despite prompt coronary reperfusion achieved with either thrombolysis or primary percutaneous coronary intervention (PPCI). It is therefore clear that novel cardio...

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Clinical Policy Bulletin: Remote Ischemic Conditioning

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Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury (IRI). It describes an endogenous phenomenon in which the application of one or more brief cycles of non-lethal ischemia and reperfusion to an organ or tissue protects a remote organ or tissue from a sustained episode of lethal IRI. Al...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Medicine

سال: 2013

ISSN: 1558-2027

DOI: 10.2459/jcm.0b013e328359dd7b