Protection of Mouse Thymus against Cobalt-60 Radiation by 2-Mercaptopropionylglycine (MPG)

Protection of mouse thymus against cobalt-60 radiation by 2-mercaptopropionylglycine (MPG).

Normal adult male Swiss albino mice, weighing 25 g on the average, were exposed to 500 R gamma rays from a Cobalt-60 source in the presence and absence of the chemical MPG or 2 mercaptopropionyiglycine and histological studies of thymus were conducted at various post irradiation intervals. It was found that MPG, when given 30 minutes before irradiation, protected the thymus tissue and caused an...

Toxicity of 2-mercaptopropionylglycine (MPG) on mouse liver.

Undertaken study deals with any vulnerable changes by the radioprotective drug 2-mer captopropionylglycine, after administering in variable concentration (20, 50, 100, 200 and 500 mg/kg body weight) of the liver of adult mice at 1, 3, 7 and 14 days interval. The lower doses, 20 and 50 mg/kg body-weight of MPG did not affect the liver at all while at higher doses of 100, 200 and 500 mg/kg body-w...

Chemoprotection of ovarian follicles of mice against gamma irradiation by MPG (2-mercaptopropionylglycine).

Chemical protection/Ovarian follicle/Gamma irradiation Adult virgin female Swiss albino mice were irradiated with 2.5, 5 and 10 Gy of gamma radiation in the presence and absence of the drug MPG and changes in the ovarian follicular population were scored at various post irradiation intervals of 3 hours to 14 days. The results indicate that the drug has partially prevented the rapid reduction in...

Multicurie Cobalt 60 Units for Radiation Therapy.

Radiation protection properties of Myrtus communis against oxidation caused by whole-body exposure of mice

Introduction: Exposure to ionizing radiation can be through direct hit or water radiolysis lead to oxidation in biological systems. In this study, the protective effect of Myrtus Communis aqueous extract on structural changes and oxidative stress in red blood cells and plasma proteins was examined after receipt of ionizing radiation. Materials and Methods: wis...