Proteases commit microbicide

Proteases commit microbicide

Proteases commit microbicide hite blood cells use proteases to kill their targets, according to new results from Emer Reeves, Hiu Lu, Anthony Segal (University College, London, England), and colleagues. The findings contradict previously accepted notions that reactive oxygen species (ROSs) are the killing agents. ROSs like superoxide are produced by NADPH oxidase activity when white blood cells...

TO COMMIT or NOT TO COMMIT ?

Rectal microbicide development.

The last few years have seen important progress in demonstrating the efficacy of oral pre-exposure prophylaxis, vaginal microbicides, and treatment as prevention as effective strategies for reducing the risk of acquiring or transmitting HIV infection. There has also been significant progress in the development of rectal microbicides. Preclinical non-human primate studies have demonstrated that ...

Two-Phase Commit Processing with Restructured Commit Tree

Extensive research has been carried out in search for an ef cient atomic commit protocol and many optimizations have been sug gested to improve the basic two phase commit protocol either for the normal or failure case Of these optimizations the read only optimiza tion is the best known and most widely used whereas the attening of the commit tree optimization is the most recent one proposed for ...

A New Presumed Commit Optimization for Two Phase Commit

Two phase commit PC is used for coordinating the commitment of transactions in distributed systems The preferred PC optimization is the presumed abort variant which reduces the number of messages when transac tions are aborted and eliminates the coordinator s need to retain information about aborted transactions The presumed commit PC variant provides a larger message reduction but its coordina...