Prostaglandins in gel for abortion.

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Therapeutic abortion by intra-amniotic injection of prostaglandins.

Intra-amniotic injection of either prostaglandin F(2)alpha or prostaglandin E(2) was used in an attempt to induce therapeutic abortion in mid-pregnancy in 27 patients. Termination of pregnancy was successful in 11 out of 13 cases when prostaglandin E(2) alone was used, but in only 6 out of 14 cases when prostaglandin F(2)alpha was used. A further eight patients aborted after additional intraven...

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Knowledge of the structure and synthesis of antibodies (immunoglobulins) has developed to a remarkable degree in the last decade. Distinct classes of immunoglobulin (yG, yM, -yA, yD, yE, and their subgroups) have been identified and shown to consist of fixed numbers of light and heavy polypeptide chains organized in pairs. Each polypeptide has a segment of variable amino acid sequence; the spec...

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Single extra-amniotic injection of prostaglandin E2 in viscous gel to induce mid-trimester abortion.

In a preliminary study a single extra-amniotic injection of 1.5 mg of prostaglandin E-2 incorporated into an aqueous viscous gel was given to 24 patients aborted within 24 hours, and the mean induction-abortion interval (plus or minus S.E. of mean) was 13.5 plus or minus 1.5 hours. Vomiting occurred in seven patients, and transient severe uterine cramps, pallor, nausea, and shivering occurred i...

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ژورنال

عنوان ژورنال: BMJ

سال: 1981

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.283.6291.614-c