Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis

Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis

AIM To define clinical criteria to differentiate eosinophilic gastrointestinal disorder (EoGD) in the esophagus. METHODS Our criteria were defined based on the analyses of the clinical presentation of eosinophilic esophagitis (EoE), subepithelial eosinophilic esophagitis (sEoE) and eosinophilic esophageal myositis (EoEM), identified by endoscopy, manometry and serum immunoglobulin E levels (s...

Eosinophilic Gastrointestinal Disorders Affect More Than Just the Esophagus.

I n 1937, Dr R. Kaisjer provided the first description of eosinophilic gastroenteritis after reviewing surgical resections taken from various parts of the gastrointestinal (GI) tract (1). During the next few decades, other descriptions, again derived from whole tissue surgical specimens, followed. With the advent of flexible endoscopy in the 1960s, physicians were provided the necessary tools t...

Eosinophilic myositis Associated with Sarcocystis in Sheep

Eosinophilic Gastrointestinal Disorders

INTRODUCTION T he eosinophilic gastroenteropathies are an interesting, yet somewhat poorly defined set of disorders that by definition include the infiltration of at least one layer of the gastrointestinal (GI) tract with eosinophils. First reported over 50 years ago, the clinical spectrum of these disorders was defined solely by various case reports. As these reports became more frequent, vari...

Eosinophilic Gastrointestinal Disorders Pathology

Eosinophilic gastrointestinal disorders (EGID) are characterized pathologically by excess eosinophils in mucosal biopsies of one or multiple sites in the gastrointestinal (GI) tract, simultaneously or sequentially. Eosinophilic esophagitis (EoE) is the best characterized EGID, and in most patients it is an abnormal immune-mediated response to food antigens. Current recommendations for diagnosis...