Prophylactic antibiotic regimens in tumor surgery (PARITY) survey

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Prophylactic antibiotic regimens in tumor surgery (PARITY) survey

BACKGROUND Deep infection following endoprosthetic limb reconstruction for sarcoma of the long bones is a devastating complication occurring in 15% of sarcoma patients. Optimizing infection protocols and conducting definitive surgical trials are critical to improving outcomes. In this study, the PARITY (Prophylactic Antibiotic Regimens in Tumor Surgery) investigators aimed to examine surgeon pr...

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Prophylactic antibiotic regimens in tumour surgery (PARITY)

OBJECTIVE Clinical studies of patients with bone sarcomas have been challenged by insufficient numbers at individual centres to draw valid conclusions. Our objective was to assess the feasibility of conducting a definitive multi-centre randomised controlled trial (RCT) to determine whether a five-day regimen of post-operative antibiotics, in comparison to a 24-hour regimen, decreases surgical s...

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Prophylactic antibiotic regimens in tumour surgery (PARITY): protocol for a multicentre randomised controlled study

INTRODUCTION Limb salvage with endoprosthetic reconstruction is the standard of care for the management of lower-extremity bone tumours in skeletally mature patients. The risk of deep postoperative infection in these procedures is high and the outcomes can be devastating. The most effective prophylactic antibiotic regimen remains unknown, and current clinical practice is highly varied. This tri...

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Prophylactic antibiotic usage in cardiothoracic surgery.

(Chest 1990; 98:719-23) U se of peniolperative antibiotics for cardiothoracic surgical procedures has been established for many I However, the actual use of these agents in everyday practice is not known. The Steering Committee of the Section of Cardiothoracic Surgery sunveyed the surgical membership of the American College of Chest Physicians to determine the actual use (If prophylactic agents...

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Optimizing Prophylactic Antibiotic Practice for Cardiothoracic Surgery by Pharmacists’ Effects

Pharmacists' role may be ideal for improving rationality of drug prescribing practice. We aimed to study the impact of multifaceted pharmacist interventions on antibiotic prophylaxis in patients undergoing clean or clean-contaminated operations in cardiothoracic department. A pre-test-post-test quasiexperimental study was conducted in a cardiothoracic ward at a tertiary teaching hospital in Suz...

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ژورنال

عنوان ژورنال: BMC Musculoskeletal Disorders

سال: 2012

ISSN: 1471-2474

DOI: 10.1186/1471-2474-13-91