Properties of Pro-Inflammatory Cell Type-Specific Leukocyte Chemotactic Cytokines, Interleukin 8 (IL-8) and Monocyte Chemotactic and Activating Factor (MCAF)
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Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line
A monocyte chemotactic and activating factor (MCAF) has been purified from TNF-stimulated 8387 human fibrosarcoma cell line-conditioned media. The purified MCAF showed microheterogeneity yielding two bands on SDS-PAGE analysis. Fibrosarcoma-derived MCAF specifically competed with THP-1 (a human monocytic cell line)-derived 125I-labeled MCAF in binding to human PBMC, whereas a similar basic hepa...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 1992
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.1992.tb02080.x