Properties of equine anti-lipopolysaccharide hyperimmune plasma: Binding to lipopolysaccharide and bactericidal activity against gram-negative bacteria
نویسندگان
چکیده
منابع مشابه
Murine bactericidal/permeability-increasing protein inhibits the endotoxic activity of lipopolysaccharide and gram-negative bacteria.
Recognition of LPS by TLR4 initiates inflammatory responses inducing potent antimicrobial immunity. However, uncontrolled inflammatory responses can be detrimental. To prevent the development of septic shock during an infection with Gram-negative bacteria, the immune system has developed mechanisms to neutralize LPS by specialized proteins. In this study, we report the recombinant expression an...
متن کاملBactericidal and bacteriolytic activity of serum against gram-negative bacteria.
INTRODUCTION ............................................................. 46 MEASUREMENT OF BACTERICIDAL AND BACTERIOLYTIC ACTIVITY.................. 47 Deectio of Serum Bactericidal Activity ............................................................. 47 Deteto of Serum Bacterlolytic Activty ............................................................. 51 MECHANISM OF SERUM BACTERICIDAL AND ...
متن کاملAnti -Bacterial Activity of Punica granatum Flower Extract against Several Gram-Negative and Positive Bacteria
Background and objectives: Bacterial antibiotic resistance is a major issue in the process of infectious disease treatments. The aim of this study was an evaluation of the antibacterial activity of Punica granatum flower extract against several gram-negative and positive clinical bacterial isolates. Methods: An adequate dried flower of an endemic mature Punica granatum plant was used for ex...
متن کاملLipopolysaccharide modification in Gram-negative bacteria during chronic infection.
The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer membrane that plays a key role in host-pathogen interactions with the innate immune system. During infection, bacteria are exposed to a host environment that is typically dominated by inflammatory cells and soluble factors, including antibiotics, which provide cues about regulation of gene expression. Bacteri...
متن کاملThermodynamic analysis of the lipopolysaccharide-dependent resistance of gram-negative bacteria against polymyxin B.
Cationic antimicrobial cationic peptides (CAMP) have been found in recent years to play a decisive role in hosts' defense against microbial infection. They have also been investigated as a new therapeutic tool, necessary in particular due to the increasing resistance of microbiological populations to antibiotics. The structural basis of the activity of CAMPs has only partly been elucidated and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1987
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-24-3-187