Propargyl Radicals in Organic Synthesis

The appearance of propargyl radicals as synthetic intermediates has increased in recent years from a structural curiosity to frequent occurrence. This minireview covers the synthetically relevant organic chemistry involving intermediacy radicals. review is organized by process employed radical generation, including H-atom abstraction, propargyl-X homolyses, addition enynes, reduction polar C=X bonds, reductions stable carbocations, and metal-mediated coupling reactions. mechanisms generation reaction are discussed, applications syntheses target molecules interest.