Prolotherapy for knee osteoarthritis using hypertonic dextrose vs other interventional treatments: systematic review of clinical trials

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Erratum: Hypertonic dextrose injections (prolotherapy) in the treatment of symptomatic knee osteoarthritis: A systematic review and meta-analysis

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Hypertonic dextrose injections (prolotherapy) in the treatment of symptomatic knee osteoarthritis: A systematic review and meta-analysis.

Hypertonic dextrose injections (prolotherapy) is an emerging treatment for symptomatic knee osteoarthritis (OA) but its efficacy is uncertain. We conducted a systematic review with meta-analysis to synthesize clinical evidence on the effect of prolotherapy for knee OA. Fifteen electronic databases were searched from their inception to September 2015. The primary outcome of interest was score ch...

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Chondrogenic Effect of Intra-articular Hypertonic-Dextrose (Prolotherapy) in Severe Knee Osteoarthritis.

BACKGROUND Dextrose injection is reported to improve knee osteoarthritis (KOA)-related clinical outcomes, but its effect on articular cartilage is unknown. A chondrogenic effect of dextrose injection has been proposed. OBJECTIVE To assess biological and clinical effects of intra-articular hypertonic dextrose injections (prolotherapy) in painful KOA. DESIGN Case series with blinded arthrosco...

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The Effects of Prolotherapy With Hypertonic Dextrose Versus Prolozone (Intraarticular Ozone) in Patients With Knee Osteoarthritis

BACKGROUND Knee osteoarthritis (KOA) is a common disabling disease. Limited studies have demonstrated that prolotherapy with dextrose or with prolozone can be helpful in the treatment of patients with KOA. OBJECTIVES In the current study, we compared the results between these two treatment methods. PATIENTS AND METHODS In the current randomized clinical trial, 80 patients with mild to moder...

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the effects of prolotherapy with hypertonic dextrose versus prolozone (intraarticular ozone) in patients with knee osteoarthritis

conclusions prolotherapy with dextrose and with prolozone result in the same pain relief or functional improvement in patients with mild to moderate koa. results in the two groups, the pain intensity and womac scores significantly decreased and increased, respectively (p < 0.001). however, there was no significant difference between the two groups. background knee osteoarthritis (koa) is a comm...

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ژورنال

عنوان ژورنال: Advances in Rheumatology

سال: 2019

ISSN: 2523-3106

DOI: 10.1186/s42358-019-0083-7