Prolonged Membrane Depolarization Enhances Midbrain Dopamine Neuron Differentiation via Epigenetic Histone Modifications
نویسندگان
چکیده
منابع مشابه
Genetic and epigenetic control of midbrain dopaminergic neuron development.
The relatively few dopaminergic (DA) neurons in the mammalian brain regulate many important neural functions, including motor integration, neuroendocrine hormone release, cognition, emotive behaviors and reward. A number of laboratories, including ours, have contributed to unravel the mechanisms of DA phenotype induction and maturation and elucidated the role of epigenetic factors involved in s...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2011
ISSN: 1066-5099
DOI: 10.1002/stem.739