Prolonged diabetic ketoacidosis due to <scp>SGLT2</scp> inhibitor use and low‐carbohydrate diet

A 59-year-old gentleman was admitted with diabetic ketoacidosis (DKA). His medication history included a sodium-glucose co-transporter 2 (SGLT2) inhibitor for the past six years. Relevant includes undertaking low-carbohydrate diet four months. In hospital he required fixed rate insulin infusion 25 hours and variable total of 32 to manage his ketonaemia. He received concomitant dextrose oral nutritional supplements throughout course admission replenish likely depleted glycogen stores in liver as result diet. The case highlights importance identifying DKA early treating underlying cause. It also potential increasing prevalence which may occur more patients are prescribed SGLT2 inhibitors adhere carbohydrate-restricted diets. Copyright © 2023 John Wiley & Sons.