Proliferation of mitochondria during the cell cycle of the human cell line (HL-60).

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Proliferation of mitochondria during the cell cycle of the human cell line (HL-60)

Using rhodamine 123 to stain mitochondria of the human cell line HL-60, we have followed their increase over the cell cycle by flow cytometry. A near-linear synthesis of mitochondrial mass was shown to occur over the cell cycle. A comparison with the cell's DNA synthesis pattern obtained by the same technique established a common time-base. The mitochondrial synthesis curve changes with culture...

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Hematopoietic cellular interaction was investigated in a coculture of the human clonal marrow stromal line, KM-102, and the myeloid leukemia cell line, HL-60. In the coculture, a large number of HL-60 cells remained in the supernatant but some of them became firmly attached to KM-102 cells. The attached HL-60 cells showed little positive reaction in the NBT test when the culture was supplemente...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1981

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.89.2.256