منابع مشابه
Prolactin secreting pituitary carcinoma.
A man with a prolactin secreting pituitary carcinoma was treated by surgery and radiotherapy. Persistent hyperprolactinaemia partially responded to oral bromocriptine for four years. Serum prolactin then rose considerably with rapid, invasive tumour recurrence. Cytotoxic chemotherapy halted tumour progression for twelve months before fatal spread throughout the brain. Failure to normalise serum...
متن کاملProlactin Secreting Pituitary Adenomas
Correspondence to: Ioana Muntean, e-mail: [email protected] ABSTRACT. Hyperprolactinemia has different etiologic forms, among them, the prolactin-secreting pituitary tumors represent an important entity. In our study, were analyzed the clinical aspects, diagnostic procedures and therapeutical approach of 31 cases of prolactinomas (F/M ratio = 27/4) hospitalized in the Clinic of Endocrinol...
متن کاملHormonal control of pituitary prolactin-secreting tumors.
Prolactin secreting adenomas (prolactinomas) are the most prevalent form of pituitary tumors in humans. Prolactinomas have been linked to estrogen exposure in humans and animals. However, the mechanism by which estrogen increases mitogenesis in lactotropes, as well as other estrogen responsive cells, is not well understood. Given the complex nature of steroid hormones and their wide array of ac...
متن کاملSynchronous GH- and prolactin-secreting pituitary adenomas
UNLABELLED Pituitary adenomas are usually solitary lesions. Rarely, patients may present with two distinct pituitary tumors. We report a case of synchronous secretory pituitary adenomas in a woman who initially presented with elevated prolactin levels. She was initially treated with cabergoline, but, after many years, she began developing symptoms consistent with acromegaly. Imaging revealed tw...
متن کاملGAL3 protein expression is related to clinical features of prolactin-secreting pituitary microadenoma and predicts its recurrence after surgical treatment.
BACKGROUND Previous in vitro study showed that Galectin-3 (Gal-3) protein plays an important role in pituitary tumorigenesis, however, the association of Gal-3 expression with the clinical feature and prognosis of pituitary tumor in a clinical setting remains unknown. METHODS We enrolled 220 patients with prolactin-secreting pituitary adenomas (PA) who previously had transsphenoidal pituitary...
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ژورنال
عنوان ژورنال: Journal of Craniofacial Surgery
سال: 2017
ISSN: 1049-2275
DOI: 10.1097/scs.0000000000003663