PROLACTIN-Deficiency in Adult Offspring of Diabetic Mothers
نویسندگان
چکیده
منابع مشابه
PROLACTIN-Deficiency in Adult Offspring of Diabetic Mothers
Maternal diabetes induces fetal alterations, resulting in lasting consequences for the glucose tolerance of the offspring over several generations. In our experimental rat model, circulating prolactin, oestradiol, progesterone and corticosterone levels, known to influence insulin secretion and action, are determined in plasma of female adult offspring of mildly and severely diabetic mothers. Pr...
متن کاملEarly growth in offspring of diabetic mothers.
OBJECTIVE By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years. RESEARCH DESIGN AND METHODS Anthropometric measures (z scores) from birth, 1.5 years, and 7.7 years in Pima Indian children were compared by mater...
متن کاملIncreased blood pressure in the offspring of diabetic mothers.
Studies were conducted in rats to determine the effect of maternal diabetes and the consequent hyperglycemia on cardiovascular function in the offspring. Diabetes was induced in pregnant Wistar rats through streptozotocin injection (50 mg/kg). Cardiovascular parameters were measured in 2-mo-old offspring animals of diabetic (OD, n=12) and control rats (OC, n=8). Arterial pressure (AP), heart ra...
متن کاملOffspring of Chronic Alcoholic Mothers
same observers (K. J. and D. W. S.). Four of these children were recognised as having a similar pattern of altered growth and morphogenesis. Thereafter, two other children were ascertained by the abnormal features identified in the first four patients, while the remaining two affected children were ascertained because their mothers were chronically alcoholic. The mothers of the affected patient...
متن کاملSecular trends in birth weight, BMI, and diabetes in the offspring of diabetic mothers.
OBJECTIVE The offspring of mothers who had diabetes during pregnancy experience increased risk later of diabetes and obesity later. We hypothesized that, in light of the historical improvements in the management of diabetes during pregnancy, these late consequences of the early environment might be diminishing with time. RESEARCH DESIGN AND METHODS Birth weight and information on BMI and gluc...
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ژورنال
عنوان ژورنال: International Journal of Experimental Diabetes Research
سال: 2000
ISSN: 1560-4284
DOI: 10.1155/edr.2000.31