Progressive Macular Hypomelanosis Successfully Treated with Topical Clindamycin and Benzoyl Peroxide

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[Progressive macular hypomelanosis successfully treated with topical clindamycin and benzoyl peroxide].

Progressive macular hypomelanosis is an acquired skin pigmentation disorder that was initially thought to be related to racial characteristics, but is currently more often associated with the presence of Propionibacterium acnes. A 23-year-old woman was seen for the progressive appearance over a 5-year period of asymptomatic whitish lesions on the trunk (Figures 1A and 2). The lesions were poorl...

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The use of lymecycline and benzoyl peroxide for the treatment of progressive macular hypomelanosis: a prospective study.

Progressive macular hypomelanosis is a dermatosis of uncertain etiology. The participation of Propionibacterium acnes has been suggested in view of the response achieved following therapy with drugs that are active against this bacterium. This report describes a series of thirteen patients with progressive macular hypomelanosis who were treated with an association of lymecycline and benzoyl per...

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Progressive macular hypomelanosis Guillet-Hélénon: structural and immunohistochemical findings.

of HHV-6 DNA in the myocardium, in the absence of other pathogens, suggests that the myocarditis was caused by the virus. Moreover, we suggest that the identification of the viral genome is favourable to a pathogenic relationship between the virus and the cardiac anomaly. In our case, there are pathological findings of acute, subacute and chronic myocarditis compatible with viral persistence. T...

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Comparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study.

INTRODUCTION A solubilized 5% BPO gel has been developed to enhance the bioavailability, follicular penetration, and efficacy of BPO. METHODS Sixty-five patients with moderate facial acne vulgaris were randomly assigned to apply solubilized 5% BPO gel to one facial side and 5% BPO/1% clindamycin to the contralateral side, twice daily for four or 12 weeks. RESULTS The solubilized BPO gel res...

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Propionibacterium acnes and the pathogenesis of progressive macular hypomelanosis.

BACKGROUND Progressive macular hypomelanosis is a common hypopigmentation mainly on the central parts of the trunk, predominantly in young adults, especially women. It is often mistaken for pityriasis versicolor and pityriasis alba. It occurs in all races and has been described in many parts of the world. We discovered follicular red fluorescence restricted to lesional skin. We suspected a rela...

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ژورنال

عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)

سال: 2010

ISSN: 1578-2190

DOI: 10.1016/s1578-2190(10)70850-7