Progressive hemifacial atrophy or Parry Romberg syndrome case report and literature review

Parry-Romberg syndrome is a condition characterized mainly by left-sided hemifacial atrophy that affects skin, subcutaneous tissue, muscle, and bone. The pathophysiology not established several theories have been proposed, among which lymphocytic neurovasculitis manifested as chronic vascular lesion measured incomplete endothelial regeneration stands out. actual treatment consists of autologous fat transfer, making voluminous grafts to restore symmetry improve the quality skin. An overcorrection recommended compensate for reabsorption estimated up 80%. repeated applications until correction achieved, there currently no consensus regarding preparation graft. objective this work propose an alternative conventional enriching fatty tissue with platelet-rich plasma, favors formation extracellular matrix, collagen fibers, angiogenesis in accelerated manner. We conclude use plasma significantly improves skin graft integration.