Progressive Encephalomyelitis with Rigidity and Myoclonus in an Intellectually Disabled Patient Mimicking Neuroleptic Malignant Syndrome
نویسندگان
چکیده
منابع مشابه
Progressive Encephalomyelitis with Rigidity and Myoclonus in an Intellectually Disabled Patient Mimicking Neuroleptic Malignant Syndrome
We present a case of 32-year-old male with profound mental retardation and autism spectrum disorder who had presented with seizures, rigidity and elevated creatine kinase and was initially diagnosed as neuroleptic malignant syndrome (NMS). The patient subsequently had a complicated clinical course, developing refractory status epilepticus, which lead to the eventual diagnosis of progressive enc...
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The incidence of neonatal septicaemia caused by group B streptococci in our hospital during 1980-6 was 9 1/10 000 births, which is three times higher than the average rate in the United Kingdom.2 Despite this, mortality during this period was only 5% (one death in 20 cases), which is one seventh the national average of 36%1; we ascribe this to the early antibiotic treatment of neonates with tac...
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Neuroleptic malignant syndrome (NMS) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs. NMS mainly occurs in patients treated with high-potency typical antipsychotics, but rarely caused by atypical antipsychotics. Although NMS is less common with atypical antipsychotic, but it seems that its incidence is rising due to increased administration of such drug...
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IMPORTANCE Progressive encephalomyelitis with rigidity and myoclonus is characterized by rigidity, painful muscle spasms, hyperekplexia, and brainstem signs. Recently, glycine receptor alpha 1 antibodies have been described in adult patients with progressive encephalomyelitis with rigidity and myoclonus. We describe a pediatric case. OBSERVATIONS A 14-month-old child developed startle-induced...
متن کاملProgressive encephalomyelitis with rigidity and myoclonus: a new variant with DPPX antibodies.
OBJECTIVE To describe a novel and distinct variant of progressive encephalomyelitis with rigidity and myoclonus (PERM) associated with antibodies directed against dipeptidyl peptidase-like protein 6 (DPPX), a regulatory subunit of the Kv4.2 potassium channels on the surface of neurons. METHODS Case series describing the clinical, paraclinical, and serologic features of 3 patients with PERM. A...
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ژورنال
عنوان ژورنال: Journal of Movement Disorders
سال: 2017
ISSN: 2005-940X,2093-4939
DOI: 10.14802/jmd.16058