Prognostic value of Ki-67 (MIB-1) and p53 in ependymomas
نویسندگان
چکیده
منابع مشابه
PROGNOSTIC SIGNIFICANCE OF MIB-1 (Ki-67) EXPRESSION IN PROSTATE CANCER AND MATCHED LYMPH NODE METASTASES
MIB-1 is a marker expressed only in proliferating cells. The aim of this study was to evaluate MIB-1 (Ki-67) labeling index in primary prostate cancer and matched nodal metastases for its prognostic value. Forty radical prostatectomy specimens from 2008 to 2009 were randomly selected for this study. Tumor blocks were immunostained using the monoclonal antibody MIB-1 (Dakorp. Denmark). MIB-1 exp...
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Nearly every pathologist that practices in a community hospital setting struggles with the accurate and reproducible identification of HPV effect and dysplasia in the female genital tract, and recognizes the fact that in certain situations these conditions can be very difficult to distinguish from reactive changes. Last month in the ProPath "Focus on Immunohistochemistry", we reviewed the poten...
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OBJECTIVE To assess the potential usefulness of Ki-67 antigen expression as a predictor of outcome in ovarian cancer through the analysis of MIB-1 monoclonal antibody reactivity. METHODS Cell proliferation and clinicopathologic variables were assessed in 26 patients with primary epithelial ovarian cancer who had undergone exploratory laparotomy. The expression of primary tumor proliferation r...
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Background: Medulloblastoma is the most common malignant brain tumor in children. The important factors in predicting survival are the extent of disease, proliferation index of the tumor cells, histopathologic class and the age at diagnosis. The percentage of Ki-67 positive cells reflects the proliferation of the cells and is one of the critical factors which determine the growth of the tumor....
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The expression of Ki-67 (MIB-1) and glucose transporter-1 (GLUT-1) were evaluated in patients with clinically localized prostate cancer (PC) who had undergone radical prostatectomy with curative intent. 140 low advanced PC specimens were studied. Protein expression was assessed immunohistochemically on tumour sections and expressed as a labelling index, i.e. the percentage of positively staine...
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ژورنال
عنوان ژورنال: Brain Tumor Pathology
سال: 2002
ISSN: 1433-7398,1861-387X
DOI: 10.1007/bf02482456