Prognostic Significance of Macrophage Infiltration in Leiomyosarcomas
نویسندگان
چکیده
منابع مشابه
Prognostic significance of macrophage infiltration in leiomyosarcomas.
PURPOSE Macrophages are migratory cells that are frequently recruited to the site of tumors. Their presence is associated with poor clinical outcome in a variety of epithelial malignancies. The aim of this study is to examine the prognostic significance of tumor-associated macrophages in sarcomas. EXPERIMENTAL DESIGN Global gene expression profiling data of a series of soft tissue tumors were...
متن کامل[Prognostic significance of tumor-associated macrophage infiltration in advanced epithelial ovarian carcinoma].
BACKGROUND AND OBJECTIVE Tumor-associated macrophage (TAM) infiltration promotes the progression of various malignancies. This study was to investigate the influence of TAM infiltration on the survival and prognosis of patients with ovarian cancer. METHODS The expression of CD68, a TAM-specific marker, in 67 specimens of ovarian cancer and 22 specimens of benign ovarian lesion was detected by...
متن کاملClinical significance of tumor-associated macrophage infiltration in supraglottic laryngeal carcinoma
Tumor-associated macrophages (TAMs) can elicit contrasting effects on tumor progression, depending on different tumor microenvironment. This study aimed to explore the correlation between TAM infiltration and clinicopathologic characteristics, metastasis, and prognosis of supraglottic laryngeal carcinoma. TAMs in intratumoral and peritumoral regions of 84 specimens of supraglottic laryngeal car...
متن کاملPrognostic Significance of Perirenal Infiltration in Renal Cell Carcinoma (<7 cm)
PURPOSE Pathologic stage is the most accurate prognostic factor of renal cell carcinoma. We evaluated whether perirenal fat infiltration is a significant factor in tumors 7 cm or less in size. MATERIALS AND METHODS We retrospectively reviewed the record of 164 cases of tumors 7 cm or less in size. We divided the patients into two groups according to the presence of perirenal fat infiltration ...
متن کاملZonal Difference and Prognostic Significance of Foxp3 Regulatory T Cell Infiltration in Breast Cancer
PURPOSE Forkhead box P3 (Foxp3) is known as the most specific marker for regulatory T lymphocytes, which play an important role in immune tolerance to disturb antitumor immunity. The present study aimed to investigate the prognostic significance of Foxp3 regulatory T lymphocyte (Foxp3 Treg) infiltration in breast cancer. METHODS Immunohistochemical studies with Foxp3, CD4, and CD8 were perfor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2008
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-07-1712