Progesterone and Implanting Blastocysts Regulate Muc1 Expression in Rabbit Uterine Epithelium

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Progesterone and implanting blastocysts regulate Muc1 expression in rabbit uterine epithelium.

Mammalian uteri are unreceptive to blastocyst implantation except during a relatively brief period. The transmembrane, cell surface mucin, Muc1, is present on epithelial cells of nonreceptive uteri in various species and has been demonstrated to have antiadhesive properties. These activities of Muc1 may prevent interaction of the embryonic trophoblast cells with the uterine epithelium. A previo...

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Uteroglobin (or blastokinin) is a specific protein produced by rabbit endometrium when stimulated by exogenous or endogenous progesterone (Schwick, 1965; Beier, 1968a, b; Krishnan & Daniel, 1967; Urzua, Stambaugh, Flickinger & Mastroianni, 1970; Arthur & Daniel, 1972; Bullock & Connell, 1973). The protein is known to bind steroids, particularly progesterone (Urzua et al., 1970; Arthur & Daniel,...

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On necropsy of a 24 months age Dutch female rabbit the uterine horns seems enlarged with a nodular appearance. On the cut surface of the uterus as well as heart wall, white firm masses with a cauliflower- like surface was observed. No other important gross lesions were found in other organs. In histopathological examination of the uterus typical microscopic changes were those of adenocarcinoma....

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Electron Microscopy of the Uterine Epithelium in the Rabbit

The ultrastructure of the uterine epithelium has been studied in estrous, ovariectomized, pregnant, and pseudopregnant rabbits. Tissue for light microscopy was fixed in Bouin's solution and stained with hematoxylin and eosin, by the periodic acid-Schiff (PAS) method, and with methylene blue. Tissue for electron microscopy was fixed in 1 per cent osmium tetroxide in White's saline and embedded i...

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expression of e-cadherin, leukemia inhibitory factor and progesterone receptor in mouse blastocysts after ovarian stimulation

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ژورنال

عنوان ژورنال: Endocrinology

سال: 1998

ISSN: 0013-7227

DOI: 10.1210/en.139.1.266