PROGENS-HbA 1c study: safety and effectiveness of premixed recombinant human insulin (Gensulin M30)

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PROGENS-HbA1c study: safety and effectiveness of premixed recombinant human insulin (Gensulin M30)

INTRODUCTION Insulin analogues have gained widespread popularity. However, in many countries the use of these drugs is limited by their relatively high cost, so there is still a need for more cost-effective human insulin therapies. The aim of the study was to assess the effectiveness and safety of the premixed recombinant human insulin (rhuI) Gensulin M30 in a real-life setting. MATERIAL AND ...

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Fat consumption and HbA(1c) levels: the EPIC-Norfolk study.

OBJECTIVE To describe the relationship between total dietary fat and the pattern of fat intake and HbA(1c). RESEARCH DESIGN AND METHODS In this cross-sectional study, 2,759 men and 3,464 women (40-78 years of age) without a previous diagnosis of type 2 diabetes were recruited from a population-based sampling frame. Diet was assessed using a self-reported semiquantitative food frequency questi...

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Interpretation of hemoglobin A(1c) (HbA(1c)) values among diabetic patients: implications for quality specifications for HbA(1c).

BACKGROUND Few studies have examined patients' views, knowledge, and understanding of glycohemoglobin A(1c) (HbA(1c)) testing. We explored such issues in patients with type 1 diabetes and used their statements to estimate analytical quality specifications for HbA(1c) testing. METHODS We recruited 201 patients from a hospital outpatient clinic. A questionnaire was used to collect information o...

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Is HbA(1c) affected by glycemic instability?

OBJECTIVE HbA(1c) is a standard clinical assessment of glycemia and the basis of most data relating glycemic control to complications. It remains unclear, however, whether HbA(1c) is affected by glycemic variation and mean glycemia. RESEARCH DESIGN AND METHODS To test this question, we analyzed the statistical relationship between HbA(1c) levels and glycemic variability as measured by self-mo...

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Difficulties in interpreting HbA(1c) results.

Glycated hemoglobin (HbA(1c)) is a parameter broadly employed in the assessment of glycemic control in diabetes. The 2010 "Standards of medical care in diabetes", published by the American Diabetes Association (ADA), recommended performing the HbA(1c) test at least every 6 months in patients in whom disease is clinically stable, while subjects after modifications of therapy or in whom glycemic ...

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ژورنال

عنوان ژورنال: Archives of Medical Science

سال: 2016

ISSN: 1734-1922

DOI: 10.5114/aoms.2016.61910