Profilin—A master coordinator of actin and microtubule organization in mammalian cells

The last two decades have witnessed a tremendous increase in cell biology data. Not least is this true for studies of the dynamic organization microfilament and microtubule systems animal cells where analyses molecular components their interaction patterns deepened our understanding these complex force-generating machineries. Previous observations cross-talk between now led to realization existence several intricate mechanisms operating maintain coordinated cellular organization. In short review, we relate development by discussing new results concerning function actin regulator profilin 1 as control component microfilament-microtubule cross-talk.