منابع مشابه
Prodrug Design vs. Drug Design
A drug is defined as a substance which is used in the cure, relief, diagnosis, treatment, or prevention of disease. The development of any potential drug commences with the study of the biochemistry and physiology behind a disease for which pharmaceutical intervention is feasible [1]. Prodrug is a term that was first introduced by Albert to signify a pharmacologically inactive chemical moiety t...
متن کاملModern prodrug design for targeted oral drug delivery.
The molecular information that became available over the past two decades significantly influenced the field of drug design and delivery at large, and the prodrug approach in particular. While the traditional prodrug approach was aimed at altering various physiochemical parameters, e.g., lipophilicity and charge state, the modern approach to prodrug design considers molecular/cellular factors, ...
متن کاملتحلیل موتور توربوپراپ در شرایط on-design و off-design
در این رساله عملکرد یک موتور توربوپراپ که ملخ آن از نوع clark y 5868-r9 است در شرایط نقطه طرح (on- design) و خارج از نقطه طرح (off- design) مورد مطالعه قرار گرفته شده است. موتور توربوپراپ یکی از انواع موتور جت در تراست بالا و مصرف مخصوص سوخت پایین است که عدد ماخ پروازی آن هرگز از 8/. تجاوز نمی کند. دور موتور های توربوجت به حدی زیاداست که در صورت اتصال مستقیم به ملخ، سرعت نوک تیغه های ملخ به سرع...
15 صفحه اولDesign Patterns vs. Language Design
This report investigates the relationships between design patterns and programming languages. A comparison is carried out between the usual track of programming languages development and the discovery of patterns. We argue that there are fundamental di erences between the two. We o er a taxonomy of patterns based on how far they are from becoming actual language features. An observation is made...
متن کاملSynchronous Vs Asynchronous Design
Much of today’s logic design is based on two major assumptions: all signals are binary, and time is discrete. Both of these assumptions are made in order to simplify logic design. By assuming binary values on signals, simple Boolean logic can be used to describe and manipulate logic constructs. By assuming time is discrete, hazards and feedback can largely be ignored. However, as with many simp...
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ژورنال
عنوان ژورنال: Drug Designing: Open Access
سال: 2013
ISSN: 2169-0138
DOI: 10.4172/2169-0138.1000e114