Procyanidin B2 cytotoxicity to MCF-7 human breast adenocarcinoma cells
نویسندگان
چکیده
منابع مشابه
Procyanidin B2 Cytotoxicity to MCF-7 Human Breast Adenocarcinoma Cells
Procyanidins have attracted some attention due to their demonstrated chemopreventive action, a relatively new and promising strategy to prevent cancer. Breast cancer is one of the leading causes of death in women worldwide and its treatment needs improvements. The aim of this work was to verify the procyanidin dimmer B2 cytotoxic effect to MCF-7 human breast cancer cells. MCF-7 cells were cultu...
متن کاملLuteolin attenuates doxorubicin-induced cytotoxicity to MCF-7 human breast cancer cells.
Luteolin, a flavone found in some vegetables, has been reported to exhibit antioxidant, antiinflammatory, and anticancer activities. In the present study, we found that luteolin has biphasic effects on the viability of the human breast cancer cell line MCF-7. That is, cell viability increased at relatively low luteolin concentrations and decreased at relatively high concentrations. Focusing on ...
متن کاملCytotoxicity Effect of Cladribine on the MCF-7 Human Breast Cancer Cell Line
Cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. Therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-CdA) on the breast cancer cell line, MCF-7 (estrogen receptor positive, ER+). MTT assay, annexin V-Fluorescein/PI and Hoechst 33...
متن کاملMetabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells.
Insulin, which activates and modifies metabolic pathways in MCF-1 human breast cancer cells, is shown to increase the cytotoxic effect of methotrexate up to ten thousand-fold in vitro. This enhanced Cytotoxicity is not due to an increased bound intracellular drug level, an increased growth rate or an increase in S phase cells, but may involve the modification or activation of biochemical pathwa...
متن کاملAssessment of Preclinical Complications of High Glucose Using Human Breast Adenocarcinoma (mcf-7) Cells
Glucose is a simple sugar that your body relies on it to produce energy. It has been shown that high glucose is related to many long-term health problems including the kidneys, nerves, eyes and vision, risk of heart disease and stroke, erectile dysfunction in men and pregnancy complications in women. Epidemiological data have suggested an increased cancer rates in diabetic patients, for which t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 0250-474X
DOI: 10.4103/0250-474x.107070