Principal-Oscillation-Pattern Analysis of Gene Expression

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Principal-Oscillation-Pattern Analysis of Gene Expression

Principal-oscillation-pattern (POP) analysis is a multivariate and systematic technique for identifying the dynamic characteristics of a system from time-series data. In this study, we demonstrate the first application of POP analysis to genome-wide time-series gene-expression data. We use POP analysis to infer oscillation patterns in gene expression. Typically, a genomic system matrix cannot b...

متن کامل

Improving gene expression cancer molecular pattern discovery using nonnegative principal component analysis.

Robust cancer molecular pattern identification from microarray data not only plays an essential role in modern clinic oncology, but also presents a challenge for statistical learning. Although principal component analysis (PCA) is a widely used feature selection algorithm in microarray analysis, its holistic mechanism prevents it from capturing the latent local data structure in the following c...

متن کامل

Linkage analysis using principal components of gene expression data

The goal of this paper is to investigate the effect of using principal components as a data reduction method for expression data in linkage analysis. We used 45 probes normalized using the Affymetrix Global Scaling that had evidence of high heritability to estimate the first 10 principal components (PC). A genome-wide linkage scan was performed on the 45 expression values and the 10 PCs using 2...

متن کامل

Pattern Recognition Methods for Gene Expression Analysis

Computer pattern recognition is a very important field of the human knowledge with applications in complex and diversified areas. Particularly in bioinformatics, pattern recognition is applied to address a miriad of problems such as identification of important regions in DNA sequences, biological classification (diagnostic) of a tissue based on mRNA expression of thousands of genes, functional ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: PLoS ONE

سال: 2012

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0028805