Primary versus radiation-associated craniofacial osteosarcoma

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Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisons.

BACKGROUND Craniofacial osteosarcoma differs from long bone osteosarcoma in that patients are older, tumors are often low grade, and prognosis is more favorable. Although most are sporadic, some tumors occur in association with prior radiation therapy. The purpose of the current study was to compare clinicopathologic and prognostic features of primary and radiation-associated osteosarcoma. ME...

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Radiation-induced sarcomas are a well-recognized late complication of radiation therapy. We present a rare case of a periosteal osteosarcoma of the femur developing 10 years after radiation treatment for a soft tissue sarcoma to highlight the clinical and radiological features of this rare complication of therapy and to describe its management.

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Primary osteosarcoma of the talus.

Osteosarcoma OS of the talus is extremely rare, and few cases have been reported in the literature. We present a case of a 33-year-old male with painful swelling of his left ankle joint. He underwent several radiological diagnostic modalities that showed osteolytic lesion in the posterior aspect of the left talus associated with new bone formation projecting from the posterior-medial aspect of ...

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Primary osteosarcoma of the breast.

Primary osteosarcoma of the breast is a rare malignant tumour. We report such a case in a 77-year-old lady who presented with a hard lump which was clinically and mammographically indistinguishable from a calcified fibroadenoma. Wide local excision of the lesion was carried out. Detailed histological and immunohistochemical features of the tumour are described. Because there was no evidence of ...

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Primary osteosarcoma of frontal bone

Rationale:Primary osteosarcomas of the skull and skull base are rare, comprising<2% of all skull tumors. Primary osteosarcomas of the skull are aggressive neoplasms composed of spindle cells producing osteoid which have poor outcome. Patientconcerns:A 33-year-old woman was admitted to our hospital with a major complaint of a growingmass on her left frontal region of the skull for 10 months. Pri...

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ژورنال

عنوان ژورنال: Cancer

سال: 2006

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.22019