Primary surgical treatment of locally advanced breast cancer in low resource settings

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Primary surgical treatment of locally advanced breast cancer in low resource settings

•Optimum management of locally advanced breast cancer is multidisciplinary.•Neoadjuvant chemotherapy is mainstay of management.•Primary surgical treatment may be acceptable in selected patients.

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Locally advanced breast cancer.

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Cervical Cancer Prevention and Treatment in Low-Resource Settings

In a recent analysis based on the 2008 worldwide estimates of cancer compiled by the International Agency for Research on Cancer (IARC, Lyon, France)1, it was estimated that 529,512 women were diagnosed with cervical cancer corresponding to an age-standardized incidence rate (ASIR) of 15.4/100,000 and 274,967 women died of the disease, with an age-standardized mortality rate (ASMR) of 7.8/100,0...

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Vinorelbine, epirubicin, and methotrexate (VEM) as primary treatment in locally advanced breast cancer.

PURPOSE This phase II trial of VEM (vinorelbine + epirubicine + methotrexate) in the treatment of locally advanced breast cancer was conducted to obtain downstaging to allow surgery and breast conservation. PATIENTS AND METHODS This multicenter study recruited 58 patients with locally advanced breast cancer (two patients ineligible); 56 were evaluable for response and tolerance. RESULTS Dow...

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ژورنال

عنوان ژورنال: Annals of Medicine and Surgery

سال: 2016

ISSN: 2049-0801

DOI: 10.1016/j.amsu.2016.10.003