Primary sleep apnoea syndrome.

Primary sleep apnoea syndrome.

Polygraphic study in 18 men with the sleep apnoea syndrome showed central, upper airway obstructive, and mixed apnoeas. Fifty per cent of the total apnoea time was central, 33% was obstructive, and 17% was mixed. Apnoeic episodes were accompanied by oxygen desaturation, relative bradycardia and hypotonia of orofacial muscles innervated by ponto-medullary neurons. During regular breathing these ...

Obstructive Sleep Apnoea Syndrome

Obstructive Sleep Apnoea Syndrome

Sleep apnoea syndrome in Pakistan?

590 Sleep apnoea syndrome (SAS), generally characterized by sleep disturbances such as snoring, obstructed breathing during sleep, excessive day-time tiredness and fatigue, is a serious problem. It is potentially a life threatening condition, that is far more common than generally understood. It is associated with a number of diseases1, including hypertension, cerebrovascular diseases and metab...

Sleep apnoea in Scheie's syndrome.

An 18-year-old student presented with a two-year history of daytime sleepiness and noisy breathing during sleep. Both he and his brother, aged 25 years, had Scheie's syndrome, a mucopolysaccharidosis characterised by small stature, micrognathia, corneal clouding, hepatosplenomegaly, raised urinary mucopolysaccharides, and undetectable levels of alpha-L-iduronidase assayed in cultured fibroblast...