Primary sequence of the mouse ribosomal protein S8
نویسندگان
چکیده
منابع مشابه
Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution.
BACKGROUND Prokaryotic ribosomal protein S8 is an important RNA-binding protein that occupies a central position within the small ribosomal subunit. It interacts extensively with 16S rRNA and is crucial for the correct folding of the central domain of the rRNA. S8 also controls the synthesis of several ribosomal proteins by binding to mRNA. It binds specifically to very similar sites in the two...
متن کاملNucleotide sequence of a rice cDNA encoding a homolog of the eukaryotic ribosomal protein S8.
Ribosomes of eukaryotes as well as prokaryotes are highly ordered ribonucleoprotein particles that serve as the factory of protein synthesis and are built of two subunits, smaller (40s) and larger (603, composed of 70 to 80 proteins and four different rRNA molecules (Wool, 1986). Expression of genes coding for ribosomal proteins, synthesis of these proteins, and their assembly to form functiona...
متن کاملPrimary sequence of the human ribosomal protein L37a.
Mammalian ribosomes consist of 82 different proteins and several RNA molecules. Sequence analysis of ribosomal proteins is essential for structural and functional studies and for understanding the evolution of ribosomes (1). Using human lymphoblast RNA and ABC (ATP binding cassette) protein (2) specific primers, we amplified a fragment highly homologous to the rat ribosomal L37a cDNA (3, 4, 5) ...
متن کاملThe amino acid sequence of rat ribosomal protein S8 was deduced from the sequence of nucleotides in a recombinant cDNA and confirmed from the NH2- and carboxyl-terminal amino acid sequences of the protein. Ribosomal protein
The amino acid sequence of rat ribosomal protein S8 was deduced from the sequence of nucleotides in a recombinant cDNA and confirmed from the NH2and carboxyl-terminal amino acid sequences of the protein. Ribosomal protein S8 contains 207 amino acids (the Nr^-terminal methionine is removed after translation of the mRNA) and has a molecular weight of 23,928. Hybridization of the cDNA to digests o...
متن کاملMutagenesis of ribosomal protein S8 from Escherichia coli: defects in regulation of the spc operon.
The structural features of Escherichia coli ribosomal protein S8 that are involved in translational regulation of spc operon expression and, therefore, in its interaction with RNA have been investigated by use of a genetic approach. The rpsH gene, which encodes protein S8, was first inserted into an expression vector under the control of the lac promoter and subsequently mutagenized with methox...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1993
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/21.20.4845