Primary posterior capsular opacification in Indian rural population undergoing cataract surgery for hypermature senile cataract

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Primary posterior capsular opacification in Indian rural population undergoing cataract surgery for hypermature senile cataract

AIM To find out the incidence of primary posterior capsular opacification (PCO) in rural patients with a hypermature senile cataract undergoing cataract surgery. SETTINGS Tertiary eye care center in central India. DESIGN Prospective, observational, noncomparative study. MATERIALS AND METHODS Two-hundred eyes of 200 patients presenting with a hypermature cataract underwent manual small inc...

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Posterior Capsular Opacification in Preschool- and School-Age Patients after Pediatric Cataract Surgery without Posterior Capsulotomy

OBJECTIVES We aimed to evaluate the development of posterior capsular opacification (PCO) in preschool- and school-age children with cataract who underwent cataract surgery without posterior capsulotomy and anterior vitrectomy. MATERIALS AND METHODS The records of 30 eyes of 21 patients who underwent pediatric cataract surgery and intraocular lens (IOL) implantation were retrospectively revie...

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Quantification of posterior capsular opacification in digital images after cataract surgery.

PURPOSE To describe a software program developed to provide an objective assessment of the amount of posterior capsular opacification (PCO) in high-resolution digital images of the posterior capsule after cataract surgery. METHODS Images are analyzed by a set protocol of defining the area of the posterior capsule, removing the Purkinje light reflexes by intensity segmentation, contrast enhanc...

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SiRNA targeting EGFR effectively prevents posterior capsular opacification after cataract surgery

PURPOSE We investigated the effect of epidermal growth factor receptor (EGFR) siRNA on human lens epithelium (HLE) cells and the development of posterior capsular opacity (PCO). METHODS We designed EGFR siRNA and used it to knockdown the expression of EGFR in HLE cells. Cell proliferation was examined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), cell growth curve ass...

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Assessment of Posterior Capsule Opacification after Cataract Surgery

Posterior capsule opacification (PCO) is the most common long-term complication with more than 25% overall incidence within 5 years after cataract surgery of the human eye. The goal of the project described in this paper is to devise a fully automated, objective measure of grades of PCO from so-called retroillumination photographs. We review the current state of the art of existing PCO grading ...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2013

ISSN: 1177-5483

DOI: 10.2147/opth.s49396