Primary cutaneous T?cell lymphomas in childhood and adolescence

Primary cutaneous lymphomas are extranodal non-Hodgkin of T- or B- cell origin, that predominantly affect older patients but have been reported in all age groups and as early the first years life. Diagnosis is challenging requires high clinical suspicion close collaboration between dermatologists, pediatric oncologists pathologists. Skin involvement children adolescents can either be primary secondary due to an underlying nodal lymphoma. The most common encountered T-cell with mycosis fungoides being prevalent lymphoma, followed by CD30+ lymphoproliferative disorders. While share clinicopathologic characteristics juvenile adult forms, there important differences terms presentation, diagnosis treatment. hypopigmented variant seems overrepresented group. Prognosis treatment stage dependent. majority present early-stage disease respond well topical corticosteroids phototherapy.