Primary cutaneous B-cell lymphoblastic lymphoma in an elderly man

Primary cutaneous B-cell lymphoblastic lymphoma in an elderly man

Precursor B-cell lymphoblastic lymphoma (B-LBL) is an uncommon high-grade neoplasm of immature B cells. It occurs predominantly in childhood with extranodal involvement such as skin and bone. Therefore, primary cutaneous involvement in elderly adults is a very rare manifestation of B-LBL. Here, we report a 78-year-old man with B-LBL presenting as a single cutaneous lesion which was immunohistoc...

Primary cutaneous B-cell lymphoblastic lymphoma.

652 in dust and air, and this increased exposure can lead to a sensitization against this metal, even in very low doses, with risk of allergic reaction, especially in susceptible individuals. Several authors have described reactions both to nickel and palladium ions,[1-3] which has led to the thinking that the reaction is not dependent on the element itself but rather on the formation of comple...

Primary cutaneous precursor B-cell lymphoblastic lymphoma with late dissemination.

A 20-year-old woman presented with multiple painless nodular swellings on the skin of the extremities and face, without any systemic symptoms. Biopsy with immunohistochemistry revealed a diagnosis of precursor B-cell lymphoblastic lymphoma. There was no extracutaneous site of involvement. The patient denied chemotherapy and was subsequently lost to follow-up. She presented with symptomatic diss...

Primary cutaneous diffuse large B-cell lymphoma, leg type in an elderly man with human immunodeficiency virus encephalopathy.

Primary pleural precursor B-Cell lymphoblastic lymphoma

Intrathoracic lymphoblastic lymphoma (LBL) is classically of T-cell lineage, but these cases of pleural B-cell LBL suggest that this is not always the case. Despite the clinical challenges involved every attempt should be made to secure a biopsy and histological diagnosis, as we move into an era of lineage-directed therapies.