Prexige: new coxib for OA, dysmenorrhoea and acute pain
نویسندگان
چکیده
منابع مشابه
Pain and OA.
Osteoarthritis (OA), in which joint degeneration leads to a loss of mobility and function, is one of the most common causes of disability. The most prominent feature but least studied aspect of OA is joint pain. The World Health Organisation recently estimated that about 10% of the world’s population over the age of 60 years suffers from OA pain which equates to an enormous socioeconomic concer...
متن کاملDiclofenac Potassium in Acute Postoperative Pain and Dysmenorrhoea: Results from Comprehensive Clinical Trial Reports
We compared the efficacy of diclofenac potassium in unpublished clinical study reports (CSRs) and published reports to examine publication bias, industry bias, and comprehensiveness. Novartis provided CSRs of randomised double-blind trials of diclofenac potassium involving postoperative patients following third molar extraction (3 trials, n=519), gynaecological surgery (3 trials, n=679), and dy...
متن کاملManaging the pain of primary and secondary dysmenorrhoea.
Dysmenorrhoea, pain during menstruation, affects 40-95 per cent of menstruating women, and has been reported as the most common causes of regular absenteeism among young women. There are two types of dysmenorrhoea: primary and secondary. Primary dysmenorrhoea is a painful menstruation with no detectable organic disease and is more common in adolescent women. Secondary dysmenorrhoea is painful m...
متن کاملDevelopment and preliminary psychometric testing of a new OA pain measure--an OARSI/OMERACT initiative.
OBJECTIVE To evaluate the measurement properties of a new osteoarthritis (OA) pain measure. METHODS The new tool, comprised of 12 questions on constant vs intermittent pain was administered by phone to 100 subjects aged 40+ years with hip or knee OA, followed by three global hip/knee questions, the Western Ontario and McMaster Universities (WOMAC) pain subscale, the symptom subscales of the H...
متن کاملSynthesis and Determination of Chronic and Acute Thermal and Chemical Pain Activities of a New Derivative of Phencyclidine in Rats
Phencyclidine (1-(1-phenylcyclohexyl) piperidine, PCP, I) and ketamine (2-O-chlorophenyl-2-methylaminocyclohexan, II) have shown analgesic effects. Some of its derivatives were synthesized and their biological properties have been studied. In this study, a new derivative of PCP, (1-[1-(3-methoxyphenyl) (tetralyl)] piperidine, PCP-OCH3-tetralyl, III) was synthesized and the acute thermal pain ...
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ژورنال
عنوان ژورنال: Prescriber
سال: 2006
ISSN: 0959-6682,1931-2253
DOI: 10.1002/psb.422