Preventive effect of oral goshajinkigan on chronic oxaliplatin-induced hypoesthesia in rats
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چکیده
منابع مشابه
Preventive effect of oral goshajinkigan on chronic oxaliplatin-induced hypoesthesia in rats
Oxaliplatin, a widely used chemotherapeutic agent, induces peripheral neuropathy that manifests itself as two distinct phases: acute cold hyperesthesia and chronic peripheral hypoesthesia/dysesthesia. The latter is a serious dose-limiting side effect that can often lead to withdrawal of treatment. We have developed a rat model expressing both phases and used the model to investigate the action ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep16078