Prevention and Health Benefits of Prebiotics, Probiotics and Postbiotics in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most common type of in children, comprising 75–85% cases. Aggressive treatment leukemias includes chemotherapy and antibiotics that often disrupt host microbiota. Additionally, gut microbiota may play a role development progression acute leukemia. Prebiotics, probiotics, postbiotics are considered beneficial to health. The prebiotics not well understood, but inulin can be potentially used Some probiotic bacteria such as Lactobacillus shows anticancer activity vitro studies. Bifidobacterium spp., consequence inhibition growth factor signaling mitochondrial-mediated apoptosis, decrease proliferation cancer cells. Many bacterial metabolites have promising potential. available research results promising. However, more needed humans, especially child population, fully understand relationship between