Preventing acute renal failure is crucial during acute tumor lysis syndrome

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Preventing acute renal failure is crucial during acute tumor lysis syndrome

Tumour Lysis syndrome (TLS) is characterized by the massive destruction of tumoral cells and the release in the extracellular space of their content. While TLS may occur spontaneously before treatment, it usu­ ally develops shortly after the initiation of cytotoxic chemotherapy. These metabolites can overwhelm the homeostatic mechanisms and cause hyperuricemia, hyperkalemia, hyperphosphatemia a...

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Hyperuricemia and acute renal failure secondary to spontaneous tumor lysis syndrome in myelodysplastic syndrome

Background: This is a rare instance of acute renal failure caused by hyperuricemia due to spontaneous tumor lysis syndrome and the first case of spontaneous tumor lysis syndrome reported in myelodysplastic syndrome. Case Presentation: A 53-year-old man presented with abrupt oligouria. Laboratory findings on admission suggested hyperuricemia, hyperphosphatemia, hypocalcinemia, metabolic acidosis...

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Acute renal failure due to tumor lysis syndrome in a HIV seropositive patient with Castleman's disease.

podocyte as a marker for the differential diagnosis of idiopathic focal glomerulosclerosis and minimal-change nephrotic syndrome. Am J Nephrol 2000; 20: 175–179 8. Nakamura T, Ushiyama C, Suzuki S et al. Urinary podocytes for the assessment of disease activity in lupus nephritis. Am J Med Sci 2000; 320: 112–116 9. Meyer TW, Bennett PH, Nelson RG. Podocyte number predicts long-term urinary album...

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Identification of children with acute lymphoblastic leukemia at low risk for tumor lysis syndrome

Background and Objective: Tumor lysis syndrome (TLS) could occur before, during or after the initiation of chemotherapy in patients with cancers especially those with hematologic malignancies. This study was designed to determine the prevalence and predictors of TLS in children with Acute Lymphoblastic Lymphoma (ALL) and to develop a sensitive prediction rule to identify patients at low risk of...

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Acute tumor lysis syndrome: a comprehensive review.

Tumor lysis syndrome is characterized by the massive destruction of malignant cells and the release in the extra-cellular space of their content. While Tumor lysis syndrome may occur spontaneously before treatment, it usually develops shortly after the initiation of cytotoxic chemotherapy. These metabolites can overwhelm the homeostatic mechanisms with development of hyperuricaemia, hyperkalaem...

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ژورنال

عنوان ژورنال: Indian Journal of Critical Care Medicine

سال: 2007

ISSN: 0972-5229,1998-359X

DOI: 10.4103/0972-5229.32434