Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers
نویسندگان
چکیده
منابع مشابه
Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers
Cancer is characterized by uncontrolled cell growth, and the cause of different cancers is generally attributed to checkpoint dysregulation of cell proliferation and apoptosis. Recent studies have shown that non-optimal codons were preferentially adopted by genes to generate cell cycle-dependent oscillations in protein levels. This raises the intriguing question of how dynamic changes of codon ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0160463