Prevalence of integrons in Enterobacteriaceae obtained from clinical samples

Multi-drug resistant bacteria are a public health problem associated with high morbidity and mortality globally. This increasing drug resistance has been linked to gene exchange between bacteria. Integrons systems known play significant role in the acquisition dissemination of antimicrobial genes especially Gram negative Hence, this study aims evaluate integrons members Enterobacteriaceae obtained from clinical samples. Forty- nine (49) isolates identified as Escherichia coli (45), Proteus mirabilis (2), Shimwellia blattae (1), Klebsiella pneumoniae (1) were amoxicillin/clavulanate, cefuroxime, cefixime ceftazidime while 43(87.76%), 45(91.84%), 46(93.88%) 29(59.18%) these strains gentamicin, ofloxacin, ciprofloxacin nitrofurantoin, respectively. Class 1 found E. (18), (1). revealed that large proportion studied multi-drug resistant, possessed integrons. Consequently, there is need for proactive antibiotic surveillance system both healthcare community settings view reducing incidence spread different species   Key words: Enterobacteriaceae, samples integrons, multidrug resistance.