Pressor Effects of Epinephrine, Norepinephrine and Desoxycorticosterone Acetate (DCA) Weakened by Sodium Withdrawal

Pressor effects of epinephrine, norepinephrine and desoxycorticosterone acetate weakened by sodium withdrawal.

Pressor activity of desoxycorticosterone acetate in normotensive and hypertensive subjects.

Pressor effects of norepinephrine after drastic reduction of sodium intake.

The mechanisms wh(eeby, dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodiu...

Pressor Effects of Norepinephrine After Drastic Reduction of Sodium Intake

The mechanisms wh(eeby, dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodiu...

Depletion of carcass potassium in rats made hypertensive with desoxycorticosterone acetate (DCA) and with cortisone.

The hypertension which can be induced experimentally in rats by the administration of desoxycorticosterone acetate (DCA) differs from that which develops in rats given cortisone acetate in its dependence upon a liberal sodium intake (1). Not only is DCA-hypertension made more severe by providing the animals with excess sodium (2), but it fails to develop if the available supply of this cation b...