PReS-FINAL-2010: Predictive value of whole-body MRI in juvenile dermatomyositis

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PReS-FINAL-2010: Predictive value of whole-body MRI in juvenile dermatomyositis

Introduction One of the major challenges in the management of juvenile dermatomyositis (JDM) is to accurately assess disease activity in order to optimize therapeutic strategies. Whole-body(WB)-MRI enables a reliable analysis of the site (skeletal muscle, subcutaneous tissue, myofascia) and magnitude of inflammatory process throughout the entire body. By providing an accurate estimation of the ...

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PReS-FINAL-2129: Whole-body versus localized magnetic resonance imaging in the assessment of juvenile dermatomyositis

Introduction MRI represents a promising tool in the assessment of disease activity in juvenile dermatomyositis (JDM). Watersensitive sequences are very sensitive to the presence of inflammation and have the potential to support diagnosis, guide muscle biopsy and monitor treatment response. So far, all MRI studies in JDM focused on pelvic and thigh musculature. Whole-body(WB)-MRI screens the ent...

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PReS-FINAL-2131: Hunting for biomarkers in juvenile dermatomyositis

Introduction Juvenile Dermatomyositis (JDM) is a systemic autoimmune disorder in which the immune system targets the microvasculature of skeletal muscles, skin and other organs, with for the most part an unknown immunopathogenesis. Moreover, evaluation of disease activity remains challenging in juvenile dermatomyositis as muscle enzyme levels and inflammatory markers, routinely used in clinics,...

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PReS-FINAL-2008: Juvenile dermatomyositis: a report of 22 cases

Methods Patients diagnosed of Juvenile dermatomyositis in La Fe Hospital (Valencia, Spain) since June 1992 to March 2013. Dates are shown in median and interquartile range for non-parametric variables, and for parametric variables is given as mean and standard deviation. To assess response to treatment, we used Wilcoxon test for paired measures of non-parametric variables and t-student for para...

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Introduction In recent years, there has been an increasing interest in parent/child-reported outcomes (pcros) in pediatric rheumatology practice. Incorporation of these measures in patient assessment is deemed important as they reflect the parents’ and children’s perception of the disease course and the effectiveness of therapeutic interventions. Although several measures of single pcros have b...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-s2-p23