Preparation, Stereochemistry, and Antibacterial Activity of Gramicidin S Analogs ContainingN-Methyl Groups
نویسندگان
چکیده
منابع مشابه
Modulation of structure and antibacterial and hemolytic activity by ring size in cyclic gramicidin S analogs.
We have evaluated the effect of ring size of gramicidin S analogs on secondary structure, lipid binding, lipid disruption, antibacterial and hemolytic activity. Cyclic analogs with ring sizes ranging from 4 to 14 residues were designed to maintain the amphipathic character as found in gramicidin S and synthesized by solid phase peptide synthesis. The secondary structure of these peptides showed...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1991
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.64.35