Preparation, Characterization and Evaluation of a Poly Methyl Methacrylate Bone Cement Modified by Montmorillonite Loaded with Silver Nano Particles

Purpose: The aim of this study was to prepare and characterize poly methyl methacrylate (PMMA) composite bone cement filled with montmorillonite (MMT) loaded silver nanoparticles (AgNPs). Materials methods: AgNPs were synthesized by the chemical reducing method. Characterization done using Field emission scanning electron microscope (FE-SEM), X-ray diffraction analysis (XRD) Thermogravimetric (TGA). Two four weight percentages MMT powder prepared MMT/AgNPs added cement.A total 75 PMMA specimens divided into 5 groups (control group, PMMT/MMT 2%, 4%, PMMT/MMTAgNps 2% 4%). Then they tested regarding compressive strength, flexural strength antibacterial activity. Results: SEM images showed layered light spots indicating presence that confirmed XRD; while TGA its thermal stability. Compressive results revealed statistically insignificant difference between control 4% PMMA/MMT significant higher values than 2%. Statisticallyinsignificant in found concentrations within PMMA/MMT/AgNPs group. Antibacterial statistical differences all (p < 0.001). Conclusion: could be used as a controlled delivery system hold proved have effect when cement. Addition improved strength.