PREPARATION, CHARACTERISATION AND EVALUATION OF ROPINIROLE HYDROCHLORIDE LOADED CONTROLLED RELEASE MICROSPHERES USING SOLVENT EVAPORATION TECHNIQUE
نویسندگان
چکیده
منابع مشابه
Preparation and In-vitro Evaluation of Metformin Microspheres Using Non-Aqueous Solvent Evaporation Technique
Purpose: To prepare and evaluate metformin microspheres for prolonged release. Methods: Metformin microspheres were prepared by non-aqueous solvent evaporation method using various polymers, including ethylcellulose (EC), hydroxypropyl methylcellulose (HPMC), carbopol 934P (CA) and chitosan (CH). The effect of process variables, viz, drug/polymer ratio, stirring rate and type of polymer on the ...
متن کاملPreparation, characterization and evaluation of ranitidine hydrochloride-loaded mucoadhesive microspheres.
BACKGROUND Mucoadhesion enables localization of drugs to a defined region of the gastrointestinal tract through attractive interactions between polymers composing the drug delivery devices and the mucin layer of the intestinal epithelium. Thus, this approach can be used for enhancement of the oral bioavailability of the drug. OBJECTIVES The current communication deals with the development of ...
متن کاملFormulation and Evaluation of Sustained Release Microspheres of Acetazolamide by Solvent Evaporation Technique
ISSN:0975-1459 Sustained release microcapsules of acetazolamide, a short half life carbonic anhydrase inhibitor, was developed to reduce the frequency of drug administration, ease of dose adjustment and improve patient compliance. In this study, sustained release microcapsules of acetazolamide was prepared by solvent evaporation techniques using Eudragit RL/RS as polymer and particle size, enca...
متن کاملSustained release microspheres of ropinirole hydrochloride: effect of process parameters.
An emulsion solvent evaporation method was employed to prepare microspheres of ropinirole hydrochloride, a highly water soluble drug, by using ethylcellulose and PEG with the help of 32 full factorial design. The microspheres were made by incorporating the drug in a polar organic solvent, which was emulsified using liquid paraffin as an external oil phase. Effects of various process parameters ...
متن کاملPreparation and evaluation of sustained release loxoprofen loaded microspheres
The aim of present study was to formulate and evaluate the loxoprofen loaded Sustained release microspheres by emulsion solvent evaporation technique. Ethylcellulose, a biocompatible polymer is used as the retardant material. The effects of process conditions such as drug loading, polymer type and solvent type on the characteristics of microspheres were investigated. The prepared microspheres w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Sciences
سال: 2018
ISSN: 0975-1491
DOI: 10.22159/ijpps.2018v10i6.26070