Preparation and Evaluation of Ibuprofen Solid Dispersion Systems with Kollidon Particles Using a Pulse Combustion Dryer System
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چکیده
منابع مشابه
synthesis of amido alkylnaphthols using nano-magnetic particles and surfactants
we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.
15 صفحه اولChem. Pharm. Bull. 55(11) 1545—1550 (2007)
prove the dissolution property and oral bioavailability of poorly water-soluble drugs, solid dispersion methods have been extensively used and numerous approaches have been reported such as fusion, solvent evaporation, and spray-drying methods. However, these methods involve various problems. Solid dispersions prepared by fusion usually have the shortcoming of being tacky and unstable, and solv...
متن کاملDevelopment and in vitro evaluation of ibuprofen mouth dissolving tablets using solid dispersion technique.
The aim of present study was to prepare and evaluate mouth dissolving tablets of ibuprofen (IBU). Ternary solid dispersion (SD) of IBU was prepared using PEG 4000 as carrier and Tween 80 as surfactant. The SD formulations were prepared by solvent evaporation and melt solvent method by varying ratio of PEG 4000. Different weight ratio of carrier, drug and surfactant 5 : 5 : 1, 10 : 5 : 1, 25 : 5...
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Background and objectives: Carvacrol is one of the main pharmacologically active components of Thymus vulgaris essential oil which has shown several therapeutic effects. There are few works regarding the formulation of essential oils as oral solid dosage forms due to their liquid nature, stability and technical problems. The aim of this study was to combine the solid-d...
متن کاملsingle-step synthesis of multi-component spirobarbiturates using ionic liquids and synthesis of substituted pyridine filled with catalysts supported on solid substrate
in this thesis, a better reaction conditions for the synthesis of spirobarbiturates catalyzed by task-specific ionic liquid (2-hydroxy-n-(2-hydroxyethyl)-n,n-dimethylethanaminium formate), calcium hypochlorite ca(ocl)2 or n-bromosuccinimide (nbs) in the presence of water at room temperature by ultrasonic technique is provided. the design and synthesis of spirocycles is a challenging task becaus...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2007
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.55.1545