PREPARATION AND EVALUATION OF ATENOLOL-β-CYCLODEXTRIN ORALLY DISINTEGRATING TABLETS USING CO-PROCESS CROSPOVIDONE-SODIUM STARCH GLYCOLATE
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چکیده
منابع مشابه
Formulation and In-vitro Evaluation of Orally Disintegrating Tablets of Olanzapine-2-Hydroxypropyl-β-Cyclodextrin Inclusion Complex
The aim of this study was to design orally disintegrating tablets of Olanzapine and to complex Olanzapine with 2-hydroxypropyl-β- cyclodextrin with special emphasis on disintegration and dissolution studies. Phase solubility studies demonstrated the formation of 1:1 molar inclusion complex by kneading method. Tablets were prepared by using superdisintegrants namely, sodium starch glycolate, cro...
متن کاملFormulation and In-vitro Evaluation of Orally Disintegrating Tablets of Olanzapine-2-Hydroxypropyl-β-Cyclodextrin Inclusion Complex
The aim of this study was to design orally disintegrating tablets of Olanzapine and to complex Olanzapine with 2-hydroxypropyl-β- cyclodextrin with special emphasis on disintegration and dissolution studies. Phase solubility studies demonstrated the formation of 1:1 molar inclusion complex by kneading method. Tablets were prepared by using superdisintegrants namely, sodium starch glycolate, cro...
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The present study investigates the use of glyceryl palmitostearate (Precirol ATO 5 – coded PATO) as binder in orally disintegrating tablets (ODT), prepared by melt granulation. PATO has been mentioned in literature for its lipophilic nature and fine powder properties, providing excelent coating and slow release of active drugs, but it can also be used for taste masking purposes, with possible a...
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Pramipexole is the mostly prescribed drug in patients with Parkinson disease. The incidence of Parkinson disease is related to aging and mostly developed in elderly people with difficulty in swallowing or dysphagia. In the current study we aimed to develop an orally fast disintegrating tablet (ODT) of pramipexole as a preferable alternative in geriatric patients. Hence, the fast disintegration ...
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The goal of this study was to compare the pharmacokinetics of nicardipine hydrochloride orally disintegrating tablets and β-cyclodextrin inclusion complex with its conventional tablets. Forty-five rats were divided into three groups evaluating the effect of dosage forms on the pharmacokinetics of nicardipine hydrochloride. Blood samples were taken at predefined sampling points 0–24h after medic...
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ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2018
ISSN: 0975-7058
DOI: 10.22159/ijap.2018v10i5.27982